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Association of sleep and circadian patterns and genetic risk with incident type 2 diabetes: a large prospective population-based cohort study.

European journal of endocrinology - 19 Oct 2021

Li Zhi-Hao, Zhang Pei-Dong, Chen Qing, Gao Xiang, Chung Vincent C H, Shen Dong, Zhang Xi-Ru, Zhong Wen-Fang, Huang Qing-Mei, Liu Dan, Chen Pei-Liang, Song Wei-Qi, Wu Xian-Bo, Byers Kraus Virginia, Mao Chen

Abstract excerpt

OBJECTIVE: To examine the association of incident type 2 diabetes (T2D) risk with sleep factors, genetic risk, and their combination effects. DESIGN: Large prospective population-based cohort study. METHODS: This population-based prospective cohort study included 360 403 (mean (s.d.) age: 56.6 (8.0) years) participants without T2D at baseline from the UK Biobank. Genetic risk was categorised as high (highest...

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PMID: 34524977
DOI: 10.1530/EJE-21-0314

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