Article
Identification of Tumor Antigens and Immune Subtypes of Glioblastoma for mRNA Vaccine Development.
Frontiers in immunology - 1 Jan 2022
Lin Han, Wang Kun, Xiong Yuxin, Zhou Liting, Yang Yong, Chen Shanwei, Xu Peihong, Zhou Yujun, Mao Rui, Lv Guangzhao, Wang Peng, Zhou Dong
Abstract excerpt
The use of vaccines for cancer therapy is a promising immunotherapeutic strategy that has been shown to be effective against various cancers. Vaccines directly target tumors but their efficacy against glioblastoma multiforme (GBM) remains unclear. Immunotyping that classifies tumor samples is considered to be a biomarker for immunotherapy. This study aimed to identify potential GBM antigens suitable for vaccine...
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