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Enhanced immortalization, HUWE1 mutations and other biological drivers of breast invasive carcinoma in Black/African American patients.

Gene - 1 Dec 2020

Andey Terrick, Attah Michael M, Akwaaba-Reynolds Nana Adwoa, Cheema Sana, Parvin-Nejad Sara, Acquaah-Mensah George K

Abstract excerpt

Black/African-American (B/AA) breast cancer patients tend to have more aggressive tumor biology compared to White/Caucasians. In this study, a variety of breast tumor molecular expression profiles of patients derived from the two racial groupings were investigated. Breast invasive carcinoma sample data (RNASeq version 2, Reverse Phase Protein Array, mutation, and miRSeq data) from the Cancer Genome Atlas were...

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PMID: 34493366
DOI: 10.1016/j.gene.2020.100030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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