Article
Inflammatory Amplification: A Central Tenet of Uterine Transition for Labor
19 Aug 2021
Abstract excerpt
In preparation for delivery, the uterus transitions from actively maintaining quiescence during pregnancy to an active parturient state. This transition occurs as a result of the accumulation of pro-inflammatory signals which are amplified by positive feedback interactions involving paracrine and autocrine signaling at the level of each intrauterine cell and tissue. The amplification events occur in parallel...
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