Article
Evaluation of Multidrug Resistant Loop-mediated Isothermal Amplification Assay for Detecting the Drug Resistance of Mycobacterium tuberculosis.
Biomedical and environmental sciences : BES - 20 Aug 2021
Liu Chun Fa, Song Yi Meng, He Ping, Liu Dong Xin, He Wen Cong, Li Yan Ming, Zhao Yan Lin
Abstract excerpt
OBJECTIVE: To evaluate multidrug resistant loop-mediated isothermal amplification (MDR-LAMP) assay for the early diagnosis of multidrug-resistant tuberculosis and to compare the mutation patterns associated with the rpoB, katG, and inhA genes at the Chinese Center for Disease Control and Prevention. METHODS: MDR-LAMP assay was evaluated using 100 Mycobacterium tuberculosis ( Mtb) isolates obtained from the...
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