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Tunicamycin Potentiates Antifungal Drug Tolerance via Aneuploidy in Candida albicans

31 Aug 2021

Abstract excerpt

Candida albicans is a prevalent human fungal commensal and also a pathogen that causes life-threatening systemic infections. Treatment failures are frequent because few therapeutic antifungal drug classes are available and because drug resistance and tolerance limit drug efficacy.

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Identifiers

PMID: 34465026
DOI: 10.1128/mbio.02272-21

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