Article
Generation of integration-free human iPSC line LCPHi001-A from a Parkinson's disease patient carrying the RecNciI mutation in GBA gene.
Stem cell research - 1 Oct 2021
Lu Xianjie, Song Na, Wang Wei, Liu Yanming, Song Hao, Xu Li, Wang Yan, Wei Chuanfei, Chen Juanli, Yang Xiaofei, Han Fabin
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disease caused by environmental and genetic factors. The identified PD genes include SNCA, LRRK2, Parkin, DJ-1, PINK1, and ATP13A2. Mutations in the glucocerebrosidase (GBA) gene were reported to be associated with PD in different ethnic populations. Here we generated a novel induced pluripotent stem cell (iPSC) line LCPHi001-A from a PD patient carrying RecNciI...
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