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Origins and Evolution of Seasonal Human Coronaviruses

15 Jul 2022

Abstract excerpt

Four seasonal human coronaviruses (sHCoVs) are endemic globally (229E, NL63, OC43, and HKU1), accounting for 5-30% of human respiratory infections. However, the epidemiology and evolution of these CoVs remain understudied due to their association with mild symptomatology. Using a multigene and complete genome analysis approach, we find the evolutionary histories of sHCoVs to be highly complex, owing to frequent...

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PMID: 35891531
DOI: 10.3390/v14071551

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