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How clinically useful is comprehensive genomic profiling for patients with non-small cell lung cancer? A systematic review.

Critical reviews in oncology/hematology - 1 Oct 2021

Torres Gabriel Fernando, Bonilla Carlos Eduardo, Buitrago Giancarlo, Arrieta Oscar, Malapelle Umberto, Rolfo Christian, Cardona Andrés F

Abstract excerpt

Given the lack of a gold standard, the clinical usefulness of Comprehensive Genomic Profiling (CGP) has not been established. This systematic review aimed to evaluate evidence about the clinical benefit of CGP for patients with Non-small cell lung carcinoma (NSCLC). All controlled studies that evaluated the ability of CGP to detect actionable targets (ATs) reported increases in the number of samples with ATs. The...

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PMID: 34461270
DOI: 10.1016/j.critrevonc.2021.103459

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