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Article

Utility of comprehensive genomic profiling in directing treatment and improving patient outcomes in advanced non-small cell lung cancer.

BMC medicine - 1 Oct 2021

Zhao Shen, Zhang Zhonghan, Zhan Jianhua, Zhao Xin, Chen Xinru, Xiao Liyun, Wu Kui, Ma Yuxiang, Li Mengzhen, Yang Yunpeng, Fang Wenfeng, Zhao Hongyun, Zhang Li

Abstract excerpt

BACKGROUND: With the identification of new targetable drivers and the recent emergence of novel targeted drugs, using comprehensive genomic profiling in lieu of the routine testing for classic drivers in the clinical care for advanced NSCLC has been increasingly advocated. However, the key assumption justifying this practice, that comprehensive genomic profiling could lead to effective anticancer therapies and...

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Identifiers

PMID: 34592968
DOI: 10.1186/s12916-021-02089-z
PMCID: PMC8485523

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