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Autoimmunity in Wiskott–Aldrich Syndrome: Updated Perspectives

1 Aug 2021

Abstract excerpt

Wiskott-Aldrich syndrome (WAS) is an uncommon X-linked combined-immunodeficiency disorder characterized by a triad of thrombocytopenia, eczema, and immunodeficiency. Patients with WAS are also predisposed to autoimmunity and malignancy. Autoimmune manifestations have been reported in 26%-72% of patients with WAS. Autoimmunity is an independent predictor of poor prognosis and predisposes to malignancy. Development...

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PMID: 34447261
DOI: 10.2147/tacg.s213920

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