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Article

Biophysical evidence to support and extend the vitamin D-folate hypothesis as a paradigm for the evolution of human skin pigmentation.

American journal of human biology : the official journal of the Human Biology Council - 1 Apr 2022

Lucock Mark D, Jones Patrice R, Veysey Martin, Thota Rohith, Garg Manohar, Furst John, Martin Charlotte, Yates Zoe, Scarlett Christopher J, Jablonski Nina G, Chaplin George, Beckett Emma L

Abstract excerpt

OBJECTIVE: To test the "vitamin D-folate hypothesis for the evolution of human skin pigmentation." METHODS: Total ozone mapping spectrometer (TOMS) satellite data were used to examine surface UV-irradiance in a large (n = 649) Australian cross-sectional study population. Genetic analysis was used to score vitamin D- and folate-related gene polymorphisms (n = 22), along with two pigmentation gene variants...

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PMID: 34418235
DOI: 10.1002/ajhb.23667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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