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Article

Sequencing Cell-free Fetal DNA in Pregnant Women With GCK-MODY.

The Journal of clinical endocrinology and metabolism - 18 Aug 2021

Kwak Soo Heon, Powe Camille E, Jang Se Song, Callahan Michael J, Bernstein Sarah N, Lee Seung Mi, Kang Sunyoung, Park Kyong Soo, Jang Hak C, Florez Jose C, Kim Jong-Il, Chae Jong Hee

Abstract excerpt

CONTEXT: Individuals with monogenic diabetes due to inactivating glucokinase (GCK) variants typically do not require treatment, except potentially during pregnancy. In pregnancy, fetal GCK genotype determines whether treatment is indicated, but noninvasive methods are not clinically available. OBJECTIVE: This work aims to develop a method to determine fetal GCK genotype noninvasively using maternal cell-free...

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Share to Cell-Free Nucleic Acids
Share to Diabetes, Gestational

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

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Source

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Identifiers

PMID: 34406393
DOI: 10.1210/clinem/dgab265
PMCID: PMC8660061

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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