An NF‐κB‐responsive long noncoding RNA, PINT, regulates TNF‐α gene transcription by scaffolding p65 and EZH2

Abstract excerpt

Long noncoding RNAs (lncRNAs) are central regulators of the inflammatory response and play an important role in inflammatory diseases. PINT has been reported to be involved in embryonic development and tumorigenesis. However, the potential functions of PINT in the innate immune system are largely unknown. Here, we revealed the transcriptional regulation of inflammatory genes by PINT, whose expression is primarily...

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