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Limitations of 16S rRNA Gene Sequencing to Characterize Lactobacillus Species in the Upper Genital Tract

29 Jul 2021

Abstract excerpt

The endometrial cavity is an upper genital tract site previously thought as sterile, however, advances in culture-independent, next-generation sequencing technology have revealed that this low-biomass site harbors a rich microbial community which includes multiple Lactobacillus species. These bacteria are considered to be the most abundant non-pathogenic genital tract commensals. Next-generation sequencing of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34395413
DOI: 10.3389/fcell.2021.641921

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