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Article

Macrophage Polarization Modulated by Porcine Circovirus Type 2 Facilitates Bacterial Coinfection.

Frontiers in immunology - 1 Jan 2021

Zhang Wen, Fu Zhendong, Yin Hongyan, Han Qingbing, Fan Wenhui, Wang Fangkun, Shang Yingli

Abstract excerpt

Polarization of macrophages to different functional states is important for mounting responses against pathogen infections. Macrophages are the major target cells of porcine circovirus type 2 (PCV2), which is the primary causative agent of porcine circovirus-associated disease (PCVAD) leading to immense economic losses in the global swine industry. Clinically, PCV2 is often found to increase risk of other...

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Identifiers

PMID: 34394082
DOI: 10.3389/fimmu.2021.688294
PMCID: PMC8355693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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