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Evaluation of IS1245 LAMP in Mycobacterium avium and the influence of host-related genetic diversity on its application.

Diagnostic microbiology and infectious disease - 1 Dec 2021

Akapelwa Mwangala Lonah, Kapalamula Thoko Flav, Ouchi-Aizu Yuki, Hang'ombe Bernard Mudenda, Nishiuchi Yukiko, Gordon Stephen V, Solo Eddie Samuneti, Tamaru Aki, Nishimura Tomoyasu, Hasegawa Naoki, Morimoto Kozo, Fukushima Yukari, Suzuki Yasuhiko, Nakajima Chie

Abstract excerpt

Early detection and treatment are paramount for the timely control of Mycobacterium avium infections. Herein, we designed a LAMP assay targeting a widely used species-specific marker IS1245 for the rapid detection of M. avium and evaluated its applicability using human (n = 137) and pig (n = 91) M. avium isolates from Japan. The developed assay could detect as low as 1 genome copy of M. avium DNA within 30...

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PMID: 34391980
DOI: 10.1016/j.diagmicrobio.2021.115494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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