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Cell Fate Reprogramming in the Era of Cancer Immunotherapy

21 Jul 2021

Abstract excerpt

Advances in understanding how cancer cells interact with the immune system allowed the development of immunotherapeutic strategies, harnessing patients’ immune system to fight cancer. Dendritic cell-based vaccines are being explored to reactivate anti-tumor adaptive immunity. Immune checkpoint inhibitors and chimeric antigen receptor T-cells (CAR T) were however the main approaches that catapulted the therapeutic...

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PMID: 34367185
DOI: 10.3389/fimmu.2021.714822

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