Article
Validation, Implementation, and Clinical Impact of the Oncomine Myeloid Targeted-Amplicon DNA and RNA Ion Semiconductor Sequencing Assay.
The Journal of molecular diagnostics : JMD - 1 Oct 2021
Ferrone Christina K, Wong Henry, Semenuk Laura, Werunga Barnaba, Snetsinger Brooke, Zhang Xiao, Zhang Grace, Lui Janet, Richard-Carpentier Guillaume, Crocker Susan, Good David, Hay Annette E, Quest Graeme, Carson Nancy, Feilotter Harriet E, Rauh Michael J
Abstract excerpt
The identification of clinically significant genes recurrently mutated in myeloid malignancies necessitates expanding diagnostic testing with higher throughput, such as targeted next-generation sequencing. We present validation of the Thermo Fisher Oncomine Myeloid Next-Generation Sequencing Panel (OMP), targeting 40 genes and 29 fusion drivers recurrently mutated in myeloid malignancies. The study includes data...
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