Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Improving Sperm Oxidative Stress and Embryo Quality in Advanced Paternal Age Using Idebenone In Vitro—A Proof-of-Concept Study

5 Jul 2021

Abstract excerpt

Advanced paternal age is associated with increased sperm reactive oxygen species (ROS) and decreased fertilization and pregnancy rates. Sperm washing during infertility treatment provides an opportunity to reduce high sperm ROS concentrations associated with advanced paternal age through the addition of idebenone. Sperm from men aged >40 years and older CBAF1 mice (12–18 months), were treated with 5 µM and 50 µM...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34356315
DOI: 10.3390/antiox10071079

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Improving Sperm Oxidative Stress and Embryo Quality in Advanced Paternal Age Using Idebenone In Vitro—A Proof-of-Concept StudyPMID 34356315Read ↗

Sperm Oxidative Stress during In Vitro Manipulation and Its Effects on Sperm Function and Embryo DevelopmentSemantic proximity Read ↗

Infertile men older than 40 years are at higher risk of sperm DNA damageSemantic proximity Read ↗

Oxidative Stress and Reproductive Function in the Aging MaleSemantic proximity Read ↗

Impacts of Oxidative Stress and Antioxidants on Semen FunctionsSemantic proximity Read ↗

Molecular Advances in Male Infertility and Fertility: Importance of Redox Regulation and Oxidative StressSemantic proximity Read ↗

Oxidative Stress in Mouse Sperm Impairs Embryo Development, Fetal Growth and Alters Adiposity and Glucose Regulation in Female OffspringSemantic proximity Read ↗

Measuring Reactive Oxygen Species in Semen for Male Preconception Care: A Scientist PerspectiveSemantic proximity Read ↗

Deciphering the role of reactive oxygen species in idiopathic asthenozoospermiaSemantic proximity Read ↗

Utility of antioxidants during assisted reproductive techniques: an evidence based reviewSemantic proximity Read ↗

Molecular Changes Induced by Oxidative Stress that Impair Human Sperm MotilitySemantic proximity Read ↗

Mitochondria-Targeted Compounds to Assess and Improve Human Sperm FunctionSemantic proximity Read ↗

Age-Related Decline of Male Fertility: Mitochondrial Dysfunction and the Antioxidant InterventionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.