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Article

Novel factor VII gene mutations in six families with hereditary coagulation factor VII deficiency.

Journal of clinical laboratory analysis - 1 Sept 2021

Zhang Xiaoyu, Wang Shuwen, Leng Shaoqiu, Feng Qi, Zhang Yanqi, Xu Shuqian, Zhang Lei, Zhang Xinsheng, Fang Yunhai, Peng Jun, Sheng Zi

Abstract excerpt

INTRODUCTION: Hereditary human coagulation factor VII (FVII) deficiency is an inherited autosomal recessive hemorrhagic disease involving mutations in the F7 gene. The sites and types of F7 mutations may influence the coagulation activities of plasma FVII (FVII: C) and severity of hemorrhage symptoms. However, the specific mutations that impact FVII activity are not completely known. METHODS: We tested the...

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PMID: 34342048
DOI: 10.1002/jcla.23905
PMCID: PMC8418470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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