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Article

Mapping Autoantibodies in Children With Acute Rheumatic Fever

15 Jul 2021

Abstract excerpt

Background: (GAS) infection associated with significant global mortality. Pathogenesis remains poorly understood, with the current prevailing hypothesis based on molecular mimicry and the notion that antibodies generated in response to GAS infection cross-react with cardiac proteins such as myosin. Contemporary investigations of the broader autoantibody response in ARF are needed to both inform pathogenesis...

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PMID: 34335616
DOI: 10.3389/fimmu.2021.702877

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