Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subtyping of head and neck squamous cell cancers based on immune signatures.

International immunopharmacology - 1 Oct 2021

Song Dandan, Lyu Haoyu, Feng Qiushi, Luo Jiangti, Li Lin, Wang Xiaosheng

Abstract excerpt

Although head and neck squamous cell cancer (HNSCC) is one of the cancer types in which immune checkpoint inhibitors (ICIs) has achieved a certain success, only a subset of HNSCC patients respond to ICIs. Thus, identification of HNSCC subtypes responsive to ICIs is crucial. Using hierarchical clustering, we identified three subtypes of HNSCC, termed Immunity-H, Immunity-M, and Immunity-L, based on the enrichment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Heterogeneity
Share to Mutation
Share to Squamous Cell Carcinoma of Head and Neck

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Transcriptome

Share to Tumor Microenvironment

Source

Identifiers

PMID: 34332341
DOI: 10.1016/j.intimp.2021.108007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subtyping of head and neck squamous cell cancers based on immune signatures.PMID 34332341Read ↗

Comprehensive Analysis of Immune Cell Enrichment In The Tumor Microenvironment of Head And Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Integrative immune subtyping of HNSCC reveals clinically relevant phenotypes and treatment-associated transitionsSemantic proximity Read ↗

Integrative Single-Cell and Bulk Transcriptomes Analyses Identify Intrinsic HNSCC Subtypes with Distinct Prognoses and Therapeutic VulnerabilitiesSemantic proximity Read ↗

Deciphering a proliferation-essential gene signature based on CRISPR-Cas9 screening to predict prognosis and characterize the immune microenvironment in HNSCCSemantic proximity Read ↗

Characterization of tumor microenvironment and Immune infiltration in head and neck squamous cell carcinomaSemantic proximity Read ↗

Molecular Subtypes Based on Cell Differentiation Trajectories in Head and Neck Squamous Cell Carcinoma: Differential Prognosis and Immunotherapeutic Responses.Semantic proximity Read ↗

Immune landscape in molecular subtypes of human papillomavirus‐negative head and neck cancerSemantic proximity Read ↗

An Immune-Related Gene Prognostic Index for Head and Neck Squamous Cell Carcinoma.Semantic proximity Read ↗

Identification of Immune-related lncRNA Panel for Predicting Immune Checkpoint Blockade and Prognosis in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Uncovering immune checkpoint heterogeneity in oral squamous cell carcinoma using single cell RNA-sequencing data highlights three subgroups of patients with distinct immune phenotypes.Semantic proximity Read ↗

Single cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratificationSemantic proximity Read ↗

8-Gene signature related to CD8+ T cell infiltration by integrating single-cell and bulk RNA-sequencing in head and neck squamous cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.