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An Immune-Related Gene Prognostic Index for Head and Neck Squamous Cell Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2021

Chen Yue, Li Zhi-Yong, Zhou Guan-Qun, Sun Ying

Abstract excerpt

PURPOSE: To construct an immune-related gene prognostic index (IRGPI) for head and neck squamous cell carcinoma (HNSCC) and clarify the molecular and immune characteristics and the benefit of immune checkpoint inhibitor (ICI) therapy in IRGPI-defined subgroups of HNSCC. EXPERIMENTAL DESIGN: On the basis of The Cancer Genome Atlas HNSCC immune dataset (n = 546), 22 immune-related hub genes were identified by...

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PMID: 33097495
DOI: 10.1158/1078-0432.CCR-20-2166

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