Early detection of duodenal cancer by upper gastrointestinal-endoscopy in Lynch syndrome.

doi:10.1002/ijc.33753

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Article

Early detection of duodenal cancer by upper gastrointestinal-endoscopy in Lynch syndrome.

International journal of cancer - 15 Dec 2021

Vangala Deepak B, Ladigan-Badura Swetlana, Engel Christoph, Hüneburg Robert, Perne Claudia, Bucksch Karolin, Nattermann Jacob, Steinke-Lange Verena, Rahner Nils, Weitz Jürgen, Kloor Matthias, Tomann Judith, Canbay Ali, Nguyen Huu-Phuc, Strassburg Christian, Möslein Gabriele, Morak Monika, Holinski-Feder Elke, Büttner Reinhard, Aretz Stefan, Löffler Markus, Schmiegel Wolff, Pox Christian, Schulmann Karsten

Abstract excerpt

Small bowel cancer (SBC) is the malignancy with the highest standardized incidence ratio in Lynch syndrome (LS) patients. Of all SBCs, about 50% are duodenal cancers (DCs), therefore being accessible by esophago-gastro-duodenoscopy (EGD) for surveillance. We asked whether early detection of DC is possible for LS patients undergoing surveillance by EGD and if surveillance should be limited to specific subgroups....

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PMID: 34331771
DOI: 10.1002/ijc.33753

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