Article
Preventing type 1 diabetes in childhood.
Science (New York, N.Y.) - 30 Jul 2021
Dayan Colin M, Besser Rachel E J, Oram Richard A, Hagopian William, Vatish Manu, Bendor-Samuel Owen, Snape Matthew D, Todd John A
Abstract excerpt
Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing β cells of the pancreas are destroyed by T lymphocytes. Recent studies have demonstrated that monitoring for pancreatic islet autoantibodies, combined with genetic risk assessment, can identify most children who will develop T1D when they still have sufficient β cell function to control glucose concentrations without the need for...
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