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Article

CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report.

The journal of headache and pain - 28 Jul 2021

Romozzi Marina, Primiano Guido, Rollo Eleonora, Travaglini Lorena, Calabresi Paolo, Servidei Serenella, Vollono Catello

Abstract excerpt

BACKGROUND AND AIMS: Hemiplegic migraine (HM) is a rare form of migraine characterized by the presence of a motor and other types of aura. HM can be sporadic or familial. Familial hemiplegic migraine (FHM) is an autosomal dominant disorder, classified into 3 subtypes, based on the gene involved (CACNA1A in FHM1, ATP1A2 in FHM2 and SCN1A in FHM3). The clinical presentation is highly heterogeneous and some attacks...

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Identifiers

PMID: 34320921
DOI: 10.1186/s10194-021-01297-5
PMCID: PMC8317284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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