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Adaptation of African swine fever virus to HEK293T cells

27 Jul 2021

Abstract excerpt

African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious disease with high morbidity and mortality in domestic pigs. Although adaptation of ASFV to Vero cells has been investigated, the phenotypic changes and the corresponding genomic variations during adaptation of ASFV to other cell lines remain unclear. To obtain a cell-adapted ASFV strain, different cell lines were tested...

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PMID: 34314096
DOI: 10.1111/tbed.14242

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