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Article

Evaluation of Gene Knockouts by CRISPR as Potential Targets for the Genetic Engineering of the Mosquito Culex quinquefasciatus.

The CRISPR journal - 1 Aug 2021

Feng Xuechun, Kambic Lukas, Nishimoto Jared H K, Reed Floyd A, Denton Jai A, Sutton Jolene T, Gantz Valentino M

Abstract excerpt

Culex quinquefasciatus mosquitoes are a globally widespread vector of several human and animal pathogens. Their biology and behavior allow them to thrive in proximity to urban areas, rendering them a constant public health threat. Their mixed bird/mammal feeding behavior further offers a vehicle for zoonotic pathogens transmission to people and, separately, poses a threat to the conservation of insular birds. The...

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Identifiers

PMID: 34280034
DOI: 10.1089/crispr.2021.0028
PMCID: PMC8392076

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