Article
Differences in Manifestations and Gut Microbiota Composition Between Patients With Different Henoch-Schonlein Purpura Phenotypes.
Frontiers in cellular and infection microbiology - 1 Jan 2021
Zhang Yuanzhen, Xia Guizhi, Nie Xiaojing, Zeng Yugui, Chen Yi, Qian Yifang, Chen Guangming, Huang Jun, Wang Chengfeng, Zhang Chuanyin, Huang Xiaoli, Yang Yuen, Qiu Xiaojian, Yang Fang, Chen Jie, Hu Jun
Abstract excerpt
Background: Gut microbiota plays an important role in the pathogenesis of immune-mediated diseases. However, the complex pathogenesis of Henoch-Schonlein Purpura (HSP) remains elusive. This study aimed to characterize the gut microbiota in HSP patients and explore the potential association between gut microbiota composition and phenotypic changes in HSP. Methods: 16SrRNA gene sequencing and bioinformatic analyses...
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