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Mendelian randomization reveals association of gut microbiota with Henoch–Schönlein purpura and immune thrombocytopenia

26 Apr 2024

Abstract excerpt

Gut microbiota have been linked to immune thrombocytopenia (ITP) and Henoch-Schönlein purpura (HSP) in recent studies, but a cause-and-effect relationship is unclear. We used Mendelian randomization (MR) to assess causal relationships between gut microbiota and HSP/ITP using summary statistics from the GWAS dataset of the international MiBioGen and FinnGen consortium. The IVW method was used as the main...

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PMID: 38671184
DOI: 10.1007/s12185-024-03777-1

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