Metagenomic profiling reveals dominance of gram‐positive bacteria in the gut microbiome shifts associated with immunoglobulin A vasculitis (Henoch–Schönlein Purpura)

Abstract excerpt

Abstract Objectives Immunoglobulin A vasculitis (IgAV), previously known as Henoch–Schönlein purpura, is the most common vasculitis that has a classical skin manifestation of palpable purpuric rash. Factors pertinent to IgAV remain inadequately understood. Here, we aimed to examine the gut microbiome shifts associated with IgAV and its recovery. Methods Stool samples were collected from 10 children with IgAV...

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