Automated screening procedure for the phenotypes of congenital fibrinogen disorders using novel parameters, |min1|c and Ac/|min1|c, obtained from clot waveform analysis using the Clauss method.

doi:10.1016/j.cca.2021.07.012

Article

Automated screening procedure for the phenotypes of congenital fibrinogen disorders using novel parameters, |min1|c and Ac/|min1|c, obtained from clot waveform analysis using the Clauss method.

Clinica chimica acta; international journal of clinical chemistry - 1 Oct 2021

Arai Shinpei, Kamijo Tomu, Kaido Takahiro, Yoda Masahiro, Shinohara Sho, Suzuki Takeshi, Arai Nobuo, Sugano Mitsutoshi, Uehara Takeshi, Okumura Nobuo

Abstract excerpt

INTRODUCTION: Fibrinogen activity (Ac) is widely measured, but fibrinogen antigen (Ag) is measured only in specialized laboratories, so it is difficult to discriminate congenital fibrinogen disorders (CFDs) from acquired hypofibrinogenemia (aHypo). In this study, to screen for CFD phenotypes we adopted novel parameters, |min1|c and Ac/ |min1|c, and compared these with validated Ac, Ag, and Ac/Ag, and previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Automated screening procedure for the phenotypes of congenital fibrinogen disorders using novel parameters, |min1|c and Ac/|min1|c, obtained from clot waveform analysis using the Clauss method.

Abstract excerpt

Topics

Related research