Article
Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers.
Alzheimer's research & therapy - 15 Jul 2021
Hackenhaar Fernanda Schäfer, Josefsson Maria, Adolfsson Annelie Nordin, Landfors Mattias, Kauppi Karolina, Hultdin Magnus, Adolfsson Rolf, Degerman Sofie, Pudas Sara
Abstract excerpt
BACKGROUND: Leukocyte telomere length (LTL) has been shown to predict Alzheimer's disease (AD), albeit inconsistently. Failing to account for the competing risks between AD, other dementia types, and mortality, can be an explanation for the inconsistent findings in previous time-to-event analyses. Furthermore, previous studies indicate that the association between LTL and AD is non-linear and may differ depending...
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