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Article

β-Catenin Restricts Zika Virus Internalization by Downregulating Axl

14 Jul 2021

Abstract excerpt

ZIKV is an emerging pathogen with sporadic outbreaks throughout the world. The most recent outbreak in North America was associated with small brains (microcephaly) in newborns. We studied the mechanism(s) that may regulate ZIKV entry into astrocytes. Astrocytes are a critical resident brain cell population with diverse functions that maintain brain homeostasis, including neurogenesis and neuronal survival. We...

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PMID: 34260264
DOI: 10.1128/jvi.00705-21

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