Article
Circulating cell-free DNA in the peripheral blood plasma of patients is an informative biomarker for multiple myeloma relapse.
International journal of clinical oncology - 1 Nov 2021
Yasui Hiroshi, Kobayashi Masayuki, Sato Kota, Kondoh Kanya, Ishida Tadao, Kaito Yuta, Tamura Hideto, Handa Hiroshi, Tsukune Yutaka, Sasaki Makoto, Komatsu Norio, Tanaka Norina, Tanaka Junji, Kizaki Masahiro, Kawamata Toyotaka, Makiyama Junya, Yokoyama Kazuaki, Imoto Seiya, Tojo Arinobu, Imai Yoichi
Abstract excerpt
BACKGROUND: Multiple myeloma (MM) is an incurable hematological malignancy. Despite the introduction of several novel drugs, most patients relapse. Biomarkers to identify the early signs of relapse will make it possible to adjust the therapeutic strategy before the disease worsens. Although understanding genetic changes is important for the treatment of MM, currently known biomarkers of relapse, including serum...
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