Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insight into Crosstalk between Ferroptosis and Necroptosis: Novel Therapeutics in Ischemic Stroke

1 Jan 2021

Abstract excerpt

Ferroptosis is a nonapoptotic form of cell death characterized by iron-dependent accumulation of lipid hydroperoxides to lethal levels. Necroptosis, an alternative form of programmed necrosis, is regulated by receptor-interacting protein (RIP) 1 activation and by RIP3 and mixed-lineage kinase domain-like (MLKL) phosphorylation. Ferroptosis and necroptosis both play important roles in the pathological progress in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Circular RNAs in diseases
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34257829
DOI: 10.1155/2021/9991001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insight into Crosstalk between Ferroptosis and Necroptosis: Novel Therapeutics in Ischemic StrokePMID 34257829Read ↗

Ferroptosis: An emerging therapeutic target in strokeSemantic proximity Read ↗

An update on the role of ferroptosis in ischemic stroke: from molecular pathways to NeuroprotectionSemantic proximity Read ↗

Crosstalk Between Autophagy and Ferroptosis and Its Putative Role in Ischemic StrokeSemantic proximity Read ↗

Recent advances in potential therapeutic targets of ferroptosis‑associated pathways for the treatment of stroke (Review)Semantic proximity Read ↗

The Interplay between Mitochondrial Dysfunction and Ferroptosis during Ischemia-Associated Central Nervous System DiseasesSemantic proximity Read ↗

Ferroptosis, a Regulated Neuronal Cell Death Type After Intracerebral HemorrhageSemantic proximity Read ↗

Bioinformatics analysis and in vivo validation of ferroptosis-related genes in ischemic strokeSemantic proximity Read ↗

Unraveling cell death mechanisms in traumatic brain injury: dynamic roles of ferroptosis and necroptosisSemantic proximity Read ↗

Necroptosis: Who Knew There were so Many Interesting Ways to Die?Semantic proximity Read ↗

Bioinformatics Analysis Identifies Potential Ferroptosis Key Genes in the Pathogenesis of Intracerebral HemorrhageSemantic proximity Read ↗

Emerging role of miRNAs in the regulation of ferroptosisSemantic proximity Read ↗

Insight into the potential role of ferroptosis in neurodegenerative diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.