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Article

Tinker where the tinkering's good.

Trends in genetics : TIG - 1 Jul 2008

Rockman Matthew V, Stern David L

Abstract excerpt

Do general principles govern the genetic causes of phenotypic evolution? One promising idea is that mutations in cis-regulatory regions play a predominant role in phenotypic evolution because they can alter gene activity without causing pleiotropic effects. Recent evidence that revealed the genetic basis of pigmentation pattern evolution in Drosophila santomea supports this notion. Multiple mutations that disrupt...

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Identifiers

PMID: 18514359
DOI: 10.1016/j.tig.2008.04.003
PMCID: PMC2887039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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