Article
Association between serum amyloid A1 genotype and age of onset restricts to M694 homozygote familial Mediterranean fever patients in Armenia.
Clinical and experimental rheumatology - 1 Jan 2000
Kriegshäuser Gernot, Hayrapetyan Hasmik, Atoyan Stepan, Oberkanins Christian, Sarkisian Tamara
Abstract excerpt
OBJECTIVES: Familial Mediterranean fever (FMF) is an autosomal-recessive, inflammatory disorder characterised by short, recurrent attacks of fever, accompanied by pain in the abdomen, chest, or joints and complications of amyloidosis. Recently, we observed a significant association between the serum amyloid A1 (SAA1) β/β genotype and a delayed disease onset in 386 M694V homozygous FMF patients. This follow-up...
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