Article
Burden of Cardiomyopathic Genetic Variation in Lethal Pediatric Myocarditis.
Circulation. Genomic and precision medicine - 1 Aug 2021
Kontorovich Amy R, Tang Yingying, Patel Nihir, Georgievskaya Zhanna, Shadrina Mariya, Williams Nori, Moscati Arden, Peter Inga, Itan Yuval, Sampson Barbara, Gelb Bruce D
Abstract excerpt
BACKGROUND: Acute myocarditis (AM) is a well-known cause of sudden death and heart failure, often caused by prevalent viruses. We previously showed that some pediatric AM correlates with putatively damaging variants in genes related to cardiomyocyte structure and function. We sought to evaluate whether deleterious cardiomyopathic variants were enriched among fatal pediatric AM cases in New York City compared with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
