Article
Management of hereditary angioedema type I and homozygous MTHFR mutation during pregnancy.
Allergologia et immunopathologia - 1 Jan 2021
Batlle Amanda Ribeiro, do Carmo Ana Paula Possar, Galao Nirelcio, Grumach Anete S
Abstract excerpt
Hereditary angioedema (HAE) is an autosomal dominant disease, characterized by edema attacks resulting from quantitative and/or functional deficiency of the C1 inhibitor (C1-INH), which acts in controlling the complement, coagulation, fibrinolysis, and contact systems. The exacerbation of these systems results in decreased circulating levels of kallikrein and conversion of bradykinin. In addition, thrombophilia...
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