Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promotion of rs3746804 (p. L267P) polymorphism to intracellular SLC52A3a trafficking and riboflavin transportation in esophageal cancer cells.

Amino acids - 1 Aug 2021

Long Lin, Pang Xiao-Xiao, Zeng Fa-Min, Zhan Xiu-Hui, Xie Ying-Hua, Pan Feng, Wang Wei, Liao Lian-Di, Xu Xiu-E, Li Bin, Wang Li-Dong, Chang Zhi-Jie, Li En-Min, Xu Li-Yan

Abstract excerpt

Riboflavin is an essential micronutrient for normal cellular growth and function. Lack of dietary riboflavin is associated with an increased risk for esophageal squamous cell carcinoma (ESCC). Previous studies have identified that the human riboflavin transporter SLC52A3a isoform (encoded by SLC52A3) plays a prominent role in esophageal cancer cell riboflavin transportation. Furthermore, SLC52A3 gene single...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

Share to Green Fluorescent Proteins

Share to Membrane Transport Proteins

Share to Riboflavin

Source

Identifiers

PMID: 34223992
DOI: 10.1007/s00726-021-03025-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Promotion of rs3746804 (p. L267P) polymorphism to intracellular SLC52A3a trafficking and riboflavin transportation in esophageal cancer cells.PMID 34223992Read ↗

Systematic analysis of the role of SLC52A2 in multiple human cancersSemantic proximity Read ↗

Functional variation of SLC52A3 rs13042395 predicts survival of Chinese gastric cancer patients.Semantic proximity Read ↗

Polymorphism of Riboflavin Transporter (RFVT) Gene in Patients with Esophageal Cancer in Hakka Population in Southern ChinaSemantic proximity Read ↗

Plasma Riboflavin Level is Associated with Risk, Relapse, and Survival of Esophageal Squamous Cell Carcinoma.Semantic proximity Read ↗

Novel riboflavin transporter family RFVT/SLC52: identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52.Semantic proximity Read ↗

Functional SNPs in human C20orf54 gene influence susceptibility to esophageal squamous cell carcinoma.Semantic proximity Read ↗

Structure/functional aspects of the human riboflavin transporter-3 (SLC52A3): role of the predicted glycosylation and substrate-interacting sites.Semantic proximity Read ↗

Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells.Semantic proximity Read ↗

Recent advances in riboflavin transporter RFVT and its genetic disease.Semantic proximity Read ↗

Impaired riboflavin transport due to missense mutations in <i>SLC52A2</i> causes Brown‐Vialetto‐Van Laere syndromeSemantic proximity Read ↗

Complete Deletion of Slc52a2 Causes Embryonic Lethality in Mice.Semantic proximity Read ↗

Association of the plasma and tissue riboflavin levels with C20orf54 expression in cervical lesions and its relationship to HPV16 infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.