Article
Complete Deletion of Slc52a2 Causes Embryonic Lethality in Mice.
Biological & pharmaceutical bulletin - 1 Jan 2021
Jin Congyun, Matsui Yoshihiro, Yonezawa Atsushi, Imai Satoshi, Ogihara Takashi, Itohara Kotaro, Nakagawa Shunsaku, Nakagawa Takayuki, Matsubara Kazuo
Abstract excerpt
Riboflavin (vitamin B2) plays an important role in cellular growth and function. Riboflavin transporter 2 (RFVT2) is widely expressed in several tissues, especially in the brain and salivary glands, and plays an important role in the tissue disruption of riboflavin. During the last 10 years, mutations in SLC52A2 have been documented in patients with a rare neurological disorder known as Brown-Vialetto-Van Laere...
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