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Paradoxical Roles of Desmosomal Components in Head and Neck Cancer

20 Jun 2021

Abstract excerpt

Desmosomes are intercellular adhesion complexes involved in various aspects of epithelial pathophysiology, including tissue homeostasis, morphogenesis, and disease development. Recent studies have reported that the abnormal expression of various desmosomal components correlates with tumor progression and poor survival. In addition, desmosomes have been shown to act as a signaling platform to regulate the...

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PMID: 34203070
DOI: 10.3390/biom11060914

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