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Article

Novel Genetic and Molecular Pathways in Pulmonary Arterial Hypertension Associated with Connective Tissue Disease.

Cells - 13 Jun 2021

Hernandez-Gonzalez Ignacio, Tenorio-Castano Jair, Ochoa-Parra Nuria, Gallego Natalia, Pérez-Olivares Carmen, Lago-Docampo Mauro, Palomino Doza Julian, Valverde Diana, Lapunzina Pablo, Escribano-Subias Pilar

Abstract excerpt

Pulmonary Arterial Hypertension (PAH) is a severe complication of Connective Tissue Disease (CTD), with remarkable morbidity and mortality. However, the molecular and genetic basis of CTD-PAH remains incompletely understood. This study aimed to screen for genetic defects in a cohort of patients with CTD-PAH, using a PAH-specific panel of 35 genes. During recruitment, 79 patients were studied, including 59...

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Identifiers

PMID: 34199176
DOI: 10.3390/cells10061488
PMCID: PMC8231632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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