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Article

Clinical impact of re-evaluating genes and variants implicated in dilated cardiomyopathy.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Nov 2021

Stroeks Sophie L V M, Hellebrekers Debby M E I, Claes Godelieve R F, Tayal Upasana, Krapels Ingrid P C, Vanhoutte Els K, van den Wijngaard Arthur, Henkens Michiel T H M, Ware James S, Heymans Stephane R B, Brunner Han G, Verdonschot Job A J

Abstract excerpt

PURPOSE: Accurate interpretation of variants detected in dilated cardiomyopathy (DCM) is crucial for patient care but has proven challenging. We applied a set of proposed refined American College of Medical Genetics and Genomics/Association for Molecular Pathology (ACMG/AMP) criteria for DCM, reclassified all detected variants in robust genes, and associated these results to patients' phenotype. METHODS: The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34194005
DOI: 10.1038/s41436-021-01255-1
PMCID: PMC7614766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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