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Article

Primary ciliogenesis is a crucial step for multiciliated cell determinism in the respiratory epithelium

25 Jun 2021

Abstract excerpt

The alteration of the mucociliary clearance is a major hallmark of respiratory diseases related to structural and functional cilia abnormalities such as chronic obstructive pulmonary diseases (COPD), asthma and cystic fibrosis. Primary cilia and motile cilia are the two principal organelles involved in the control of cell fate in the airways. We tested the effect of primary cilia removal in the establishment of a...

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PMID: 34170075
DOI: 10.1111/jcmm.16729

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