Article
Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2022
Margaritte-Jeannin Patricia, Budu-Aggrey Ashley, Ege Markus, Madore Anne-Marie, Linhard Christophe, Mohamdi Hamida, von Mutius Erika, Granell Raquel, Demenais Florence, Laprise Catherine, Bouzigon Emmanuelle, Dizier Marie-Hélène
Abstract excerpt
BACKGROUND: Numerous genes have been associated with the three most common allergic diseases (asthma, allergic rhinitis or eczema) but these genes explain only a part of the heritability. In the vast majority of genetic studies, complex phenotypes such as co-morbidity of two of these diseases, have not been considered. This may partly explain missing heritability. OBJECTIVE: To identify genetic variants...
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