Article
Can Unlikely Neanderthal Chloride Channel CLC-2 Gene Variants Provide Insights in Modern Human Infertility?
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 19 Jun 2021
Jeworutzki Elena, Tüttelmann Frank, Rothenberg Ina, Pusch Michael, Schreiber Julian A, Kliesch Sabine, Wünsch Bernhard, Strutz-Seebohm Nathalie, Seebohm Guiscard
Abstract excerpt
BACKGROUND/AIMS: Neanderthals, although well adapted to local environments, were rapidly replaced by anatomically modern humans (AMH) for unknown reasons. Genetic information on Neanderthals is limited restricting applicability of standard population genetics. METHODS: Here, we apply a novel combination of restricted genetic analyses on preselected physiological key players (ion channels), electrophysiological...
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