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Chronic Jet Lag Exacerbates Jejunal and Colonic Microenvironment in Mice

1 Jun 2021

Abstract excerpt

Background: Evidence suggests that circadian rhythm disorder is associated with a variety of gastrointestinal diseases, and the circadian rhythm plays a key role in maintaining the homeostasis of intestinal flora. The underlying mechanisms are still not completely identified. This study was aimed to explore whether jet lag-caused circadian disruption influences gut microbiome and its metabolites. Methods: Mice...

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PMID: 34141627
DOI: 10.3389/fcimb.2021.648175

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